Hypoxia in Covid Possible Key to Effective Treatment as Ventilators Continue to Fail?
Has the answer been there all along?
Hypoxia in Covid Possible Key to Effective Treatment as Ventilators Continue to Fail?
Could it be this simple? Could a key to the complicated nature of Covid’s respiratory progression be in the hypoxia? I’m not a doctor, but there is a fairly compelling case to be made.
Early in the pandemic, we heard whispers that Covid-19 was not simply a respiratory disease exclaiming ventilators rarely had good outcomes. Yet here we are, two long and terrible years later, offering the very same NIH protocol with the very same deadly outcomes.
It now seems clear that if we miss the early treatment phase of Covid, the chance of rapid and serious disease, requiring hospital breathing interventions goes up exponentially, often with poor outcomes.
We hear stories of people suddenly unable to find breath or having rapid drops in oxygen saturation levels and our Medical Community is confounded.
Hypoxia, a common condition, sometimes referred to as Cyanosis, may hold the answers. This condition, often a symptom of more common chronic diseases, such as COPD, is easy to diagnose.
So why have they continued to pursue their one-size-fits-all experimental NIH failure of a protocol and ignored the potential clues in the hypoxia?
There has been reference in the research to the ‘Covid-19 Hypoxia Paradox’, but I wonder if it’s really a paradox at all. There have been glimpses of understanding the hypoxia element, but no broad studies funded.
One product, FDA approved to treat hypoxia, was found in a January 2021 study to be effective at inhibiting the Covid spike protein from binding to the ACE2 receptors. Blocking access to this high affinity binding site dramatically decreases Covid’s ability to replicate.
Oddly, this treatment has not been pursued on any large scale.
More intriguing, however, is this same product is commonly used to deactivate viruses in blood prior to transfusion. [1]
Think of that, a compound used to deactivate viruses and treats hypoxia, can’t possibly be worth looking into…. That product is Methylene Blue and it’s over the counter.
A common cause of hypoxia is methemoglobinemia; which, in layman’s terms, is a high rate of methemoglobin in the blood, preventing adequate oxygen distribution.
This correlates with the good outcomes cited in the study referenced above and may hold clues for treatment of acute hypoxia in Covid-19. And below, you’ll see the symptoms of methemoglobinemia mirror those of Covid-19’s respiratory distress.
Unlike hemoglobin, methemoglobin cannot bind oxygen effectively. Hence, methemoglobin is not a good transporter of oxygen from the lungs to the various parts of the body. This affects a variety of organs, which do not function well due to a lack of oxygen, including causing certain cardiovascular conditions -Dovemed.com
This does not explain why Covid would result in hypoxia or methemoglobinemia, but so little is understood about the disease, it would be foolish to dismiss. There is already plenty of anecdotal evidence of its efficacy. Understanding why can come later. They’ve already gotten so much wrong, why not let the amateurs have a go.
The good news is there’s an easy way to test for Methemoglobinemia (hypoxia). It’s probably easier to take the test than say the word.
Dovemed.com provides a great summary of the disease, symptoms, testing and more.
What is Methemoglobin and How Does it Cause Hypoxia?
Symptoms of Methemoglobinemia
· Bluish skin
· Fatigue
· Troubled breathing
· Dizziness
· Headache
· Abnormal heart rate
What is Methemoglobin?
Methemoglobin (Hb M) is a dysfunctional form of the oxygen-carrying protein hemoglobin. It may result in oxygen deficiency and further complications affecting tissue function
Oxygen is extremely important in sustaining human life. It is so important that fully one-third of the body’s 75 trillion cells are red blood cells: the vehicles for oxygen transport
The so-called “bed” of these vehicles, the storage part, is hemoglobin. Each red blood cell is 97% hemoglobin, meaning that there is a tremendous amount of hemoglobin present at any one time in the body - around 0.75 kg!
Iron is necessary to hemoglobin because it serves essential structural and functional roles. Methemoglobin is a form of hemoglobin in which iron holds on to the hemoglobin protein in a chemical form that results in abnormal oxygen exchange. A normal oxygen exchange between the hemoglobin and the tissue is required for well-functioning of the body
Unlike hemoglobin, methemoglobin cannot bind oxygen effectively. Hence, methemoglobin is not a good transporter of oxygen from the lungs to the various parts of the body. This affects a variety of organs, which do not function well due to a lack of oxygen, including causing certain cardiovascular conditions
Methemoglobin arises due to chemicals, radiation, and drugs (such as nitrates and anesthetics), or acquired enzyme deficiencies. Infants are more prone to developing high methemoglobin levels called methemoglobinemia
The Methemoglobin Blood Test helps determine the levels of methemoglobin in blood. It is used to diagnose methemoglobinemia
What are other Names for this Test? (Equivalent Terms)
Hb M Blood Test
Hemoglobin M Blood Test
What is the Significance of the Methemoglobin Blood Test Result?
A high value (greater than 20%) for the Methemoglobin Blood Test may point to a diagnosis of methemoglobinemia [2]
While I’m not a doctor, this seems like a low-cost, low-risk, worthwhile thread to pursue in the face of what has thus far been an utter failure. There’s only upside.
Our leaders in government and academic medicine have come up empty, looking only to big pharma and costly experiments. Why else leave currently effective, safe and time-tested potentials on the shelf?
I hope the medical establishment will begin looking past their paychecks and protocol protections and do a little independent inquiry, like the ‘practitioners’ they were intended to be.
As always, do your own research. In this day and age, it could not BE more important!
To your health!
[1]Methylene Blue Inhibits the SARS-CoV-2 Spike–ACE2 Protein-Protein Interaction–a Mechanism that can Contribute to its Antiviral Activity Against COVID-19 - PMC (nih.gov)
[2] Methemoglobin Blood Test (dovemed.com)
Additional Science and information on Methylene Blue:
Study explains potential causes for 'happy hypoxia' condition in COVID-19 patients: Findings could prevent unnecessary intubation -- ScienceDaily
Methylene Blue: COVID-19 At-Home Treatment | Alive-N-Healthy (alivenhealthy.com)
Anticancer activity of methylene blue via inhibition of heat shock protein 70 – ScienceDirect